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Central oxytocin administration reduces food intake in lean and DIO rats. Food intake and body weight change in rats maintained on a LFD (A, C) compared with a HFD (B, C) following 3rd ventricle (3V) administration of vehicle or oxytocin (1 μg) administered immediately prior to dark cycle onset. Data represent means ± SE. *P < 0.05 vs. vehicle.
