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Production and metabolism of formate. THF, tetrahydrofolate; BHMT, betaine-homocysteine S-methyltransferase; CBS, cystathionine-β-synthase; CGL, cystathionine-γ-lyase; DMG, dimethylglycine; DMGD, dimethylglycine dehydrogenase; FDH, 10-formyltetrahydrofolate dehydrogenase; FTS, 10-formyltetrahydrofolate synthase; GDC, glycine decarboxylase; MS, methionine synthase; MTHFR, methylenetetrahydrofolate reductase; SDH, sarcosine dehydrogenase; SHMT, serine hydroxymethyltransferase.
