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Time course of formate excretion in urine (normalized to creatinine; A), plasma formate (B), and plasma Hcy (C) in rats fed a folate-deficient (open bars) or control diet (black bars). The rats were placed on the diet at ≈70 g of body wt. Each data point represents the mean ± SD; n = 3. *Significant difference between control and deficient diet (P < 0.05).
