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. 2011 Sep 27;302(1):E87–E102. doi: 10.1152/ajpendo.00218.2011

Fig. 7.

Fig. 7.

Effect of exendin-4 on secretion and metabolic profiles of isolated cultured mouse islets. A: insulin release patterns with glucose stimulation using stepwise increases in glucose concentrations in the absence and presence of 50 nM exendin-4 (n = 3). B: effect of exendin-4 on islet respiration (n = 3). C: effect of exendin-4 on glucose usage of mouse islets as a function of glucose concentrations (n = 3–4). D: ATP production/insulin secretion diagram. E: physiologically relevant comparison of ATP production/insulin secretion diagram of exendin-4-treated islets and controls. F: physiologically relevant comparison of ATP production/insulin secretion diagram in the presence of exendin-4 or piragliatin.