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. 2001 May 1;98(10):5728–5733. doi: 10.1073/pnas.091533398

Table 1.

BAP111 specifically interacts with brm in vivo

Progeny Eye score
1 2 3 4 5 6
Expressing brmK804R
 FM7 live 0 12 19 11 0 0
 FM7 pharate 0 0 6 2 0 0
 FM7 total 0 12 25 13 0 0
 Df(1)18.1.15 live 0 3 1 5 2 3
 Df(1)18.1.15 pharate 0 0 0 9 3 18
 Df(1)18.1.15 total 0 3 1 14 5 21
 Df(1)18.1.15, [w+, UAS-BAP111] live 4 74 62 9 3 0
 Df(1)18.1.15, [w+, UAS-BAP111] pharate 0 2 2 0 0 0
 Df(1)18.1.15, [w+, UAS-BAP111] total 4 76 64 9 3 0
Expressing brmK804R
 FM7 live 0 4 13 23 0 0
 FM7 pharate 0 0 6 4 0 0
 FM7 total 0 4 19 27 0 0
 Df(1)18.1.15 live 0 0 0 5 5 4
 Df(1)18.1.15 pharate 0 0 0 8 11 17
 Df(1)18.1.15 total 0 0 0 13 16 21
 Df(1)18.1.15, [w+, UAS-BAP111ΔHMG] live 0 7 8 24 11 1
 Df(1)18.1.15, [w+, UAS-BAP111ΔHMG] pharate 0 0 3 3 0 1
 Df(1)18.1.15, [w+, UAS-BAP111ΔHMG] total 0 7 11 27 11 2
Expressing ISWIK159R
 FM7 live 0 22 14 0 0 0
 FM7 pharate 0 3 3 0 0 0
 FM7 total 0 25 17 0 0 0
 Df(1)18.1.15 live 13 19 20 0 0 0
 Df(1)18.1.15 pharate 2 2 0 0 0 0
 Df(1)18.1.15 total 15 21 20 0 0 0

Eyes of female progeny from crosses described in Methods were scored for defects. Numerical scores are defined as follows: 1 = wild-type eye, 2 = roughness comprising ≤50% of normal eye area, 3 = roughness comprising >50% of normal eye area, 4 = roughness of eye and eye slightly reduced in size, 5 = roughness of eye and eye size reduced by >50%, and 6 = eye absent (no recognizable omatidia). FM7 (the FM7c balancer chromosome bearing the dominant eye marker Bar) was scored as a 2. The difference in FM7c vs. Df(1)18.1.15 data is significant for the flies expressing brmK804R (P < 0.001), as is the rescue by the wild-type BAP111 transgene (P < 0.001 for Df(1)18.1.15 vs. Df(1)18.1.15, P[w+, UAS-BAP111]22-1). No significant shift was caused by the Df(1)18.1.15 in the flies expressing ISWIK159R (P < 0.10).