Skip to main content
. Author manuscript; available in PMC: 2012 Apr 17.
Published in final edited form as: J Cardiovasc Transl Res. 2010 Nov 19;4(1):82–91. doi: 10.1007/s12265-010-9241-3

Figure 2.

Figure 2

Impact of infarct mechanical properties on left ventricular function. Contour plots display variations in functional indices across the parameter space; titles in each panel provide values for the noninfarcted baseline model and acute ischemia model with normal fiber distribution and passive myocardial properties. A,B End-diastolic volume at a pressure of 10 mmHg and end-systolic volume at a pressure of 100 mmHg both decreased as infarct stiffness increased. C Isotropic stiffening provided the best systolic contractility as measured by the slope of the end-systolic pressure-volume relationship (Emax). D Anisotropic stiffening in the longitudinal direction produced the highest predicted stroke volume.