. 2012 Feb 20;9:12. doi: 10.1186/1743-7075-9-12

Table 3.

Vitamin K concentrations in serum and bone of OVX rats fed with low or high vitamin K for 6 wk¹

	Control² PK:0.14 mg/kg diet	BP² PK:0.14 mg/kg diet	PK 107 mg/kg diet	MK-4 147 mg/kg diet	MK-7 201 mg/kg diet
Serum

PK, nmol/L	0.2 ± 0.3^a	0.1 ± 0.3^a	238.0 ± 92.2^c	0.0 ± 0.2^a	1.9 ± 0.9^b

MK-4, nmol/L	0.3 ± 0.5^a	0.2 ± 0.5^a	5.8 ± 2.5^b	41.5 ± 17.7^d	3.1 ± 1.0^c

MK-7, nmol/L	ND^a	ND^a	ND^a	ND^a	31.4 ± 22.7^b

Tibia

PK, pmol/g	13.7 ± 12.5^a	20.6 ± 14.0^ab	1760.0 ± 581.0^c	23.7 ± 21.1^ab	13.4 ± 16.3^ab

MK-4, pmol/g	ND^a	ND^a	ND^a	62.4 ± 87.0^c	1.0 ± 1.7^b

MK-7, pmol/g	ND^a	ND^a	ND^a	ND^a	16.7 ± 14.0^b

¹Values are means ± SD, n = 16. ²Low vitamin K diet (Harlan Teklad, TD. 97053). ND: values were below the minimum detectable concentrations of 0.05 nmol/L or 0.05 pmol/g. ^a,b,cWhen comparing measures across the five groups, means with different letter subscripts are statistically different, P < 0.05