Skip to main content
. Author manuscript; available in PMC: 2012 Apr 17.
Published in final edited form as: Nature. 2010 Jun 3;465(7298):577–583. doi: 10.1038/nature09141

Figure 2. HIF-1 impedes DNA-damage-induced apoptosis by inhibiting CEP-1.

Figure 2

a, Wild-type or vhl-1(ok161) worms were grown on bacteria containing either an empty control RNAi vector or ced-9(RNAi). Germline apoptosis was quantified at the indicated time points beginning at the fourth larval (L4) stage. Data shown represent the average of three independent experiments ± s.d. (n > 20). b, CEP-1 western blot analysis of synchronized young adult animals. pCEP-1, phosphorylated CEP-1. β-actin was used as loading control.