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. Author manuscript; available in PMC: 2012 Jul 22.
Published in final edited form as: J Mol Biol. 2011 Jul 22;410(4):553–564. doi: 10.1016/j.jmb.2011.04.072

Table 1.

In vitro binding affinities for retroviral MA proteins and nucleic acids

Retrovirus MA
Protein
Binding Affinity Kd (M) Nucleic acid Reference
HIV 3-30 × 10−9 RNA 50mer (SELEX) 56
HIV 5 ×10−7 RNA with homology to
the pol region
54
HIV 1.5 × 10−5 ssDNA 30mer 51
HIV 5.42 × 10−7 ssDNA 20mer 50
HIV 3.25 ×10−7 minihelixLys 50
RSV 3.6 × 10−12 Viral RNA 17,18
RSV 1 × 10−7* Viral RNA 22
*

Intrinsic Kd estimated at 2.9 × 10−3 to 9.1 × 10−4 M.