Figure 3.

Anatomical and perfusion images from a patient with hypertension and diabetes mellitus and an age-matched healthy control. a | Brain volume loss. b | Extensive periventricular white matter hyperintensities. c | Reduced perfusion in the frontal and temporal regions. d | Normal brain volume. e | Absence of white matter hyperintensities. f | Normal perfusion throughout the brain. Abbreviations: 3D CASL, three-dimensional continuous arterial spin labeling; FLAIR, fluid attenuated inversion recovery; MPRAGE, T1-weighted magnetization-prepared rapid acquisition with gradient echography.