Table 2.
Unadjusted associations of neighborhood psychosocial hazards and APOE genotype with cognitive domain scores.
| Cognitive domain | NPH quartile 4 vs. quartiles 1–3 β (95% CI) |
APOE-ε4 genotype β (95% CI) |
|---|---|---|
| Language | −0.57 (−0.80, −0.35) | −0.09 (−0.21, 0.04) |
| Processing speed | −0.38 (−0.52, −0.24) | −0.07 (−.20, 0.06) |
| Eye-hand coordination | −0.43 (−0.56, −0.30) | −0.11 (−0.22, 0.00) |
| Executive function | −0.41 (−0.55, −0.28) | −0.08 (−0.18, 0.02) |
| Verbal memory & learning | −0.36 (−0.48, −0.23) | −0.10 (−0.25, 0.06) |
| Visual memory | −0.39 (−0.54, −0.23) | −0.05 (−0.20, 0.10) |
| Visuoconstruction | −0.64 (−0.85, −0.44) | −0.19 (−0.35, −0.04) |
Abbreviations: NPH, Neighborhood Psychosocial Hazards scale; APOE ε4, apolipoprotein E epsilon-4; CI, confidence interval