Table 1. Laboratory Results for the Fatal Laboratory Positive Dengue Cases, 2007, Puerto Rico.

	First Serum Specimen								Second Serum Specimen				Tissue
Case	DPO	DENV RT-PCR	DENV MAC-ELISA	DENV IgG ELISA	WNV RT-PCR	WNVMAC-ELISA	PRNT	Lepto IgM	DPO	DENV RT-PCR	DENVMAC-ELISA	DENV IgG ELISA	DPO	DENV RT-PCR	DENV IHC
1	3	DENV-3	NEG	NEG	N/A	NEG	N/A	QNS					4	POS	POS
2	5	DENV-2	POS	NEG	N/A	NEG	N/A	QNS
3	7	NEG	POS	POS	N/A	NEG	N/A	NEG	8†	NEG	NEG	POS
4	5	DENV-3	NEG	POS	N/A	NEG	N/A	QNS
5	6	DENV-1	NEG	POS	NEG	POS	D1: 32D2: 128D3: 32D4: 32WNV: 8	QNS
6	5	DENV-3	POS	POS	N/A	NEG	N/A	QNS
7	3	NEG	POS	POS	NEG	POS	D1: 64D2: >512D3: 128D4: 16WNV: 16	QNS	4	NEG	POS	POS	4	POS	POS
8	8	NEG	POS	POS	NEG	POS	D1: 256D2: 128D3: 64D4: 64WNV: 16	QNS	9†	NEG	NEG	POS	9	POS	POS
9													4	POS	POS
10	9	NEG	POS	POS	N/A	NEG	N/A	NEG
11	4	NEG	POS	POS	NEG	POS	D1: >512D2: 256D3: <128D4: 128WNV: <128	QNS

DPO = day post onset of fever; DENV = dengue virus; RT-PCR = reverse transcriptase polymerase chain reaction; MAC-ELISA = IgM antibody capture enzyme linked immunosorbent assay; ELISA = enzyme linked immunosorbent assay; WNV = West Nile virus; PRNT = plaque reduction neutralization test; IgM Lepto = IgM ELISA ImmunoDOT assay for Leptospira; IHC = immunohistochemical microscopy; NEG = negative test result; POS = positive test result; N/A = not applicable for patient; QNS = quantity not sufficient to perform test indicated.

†: These samples where whole blood collected at time of death.