Skip to main content
. 2012 Apr 17;7(4):e33772. doi: 10.1371/journal.pone.0033772

Figure 5. Suppression of in vitro migration and invasion capabilities of CL1–5 cells by DMSO treatment.

Figure 5

(A) DMSO decreases cancer cell migration ability, as assessed by a scratch wound healing assay. The track was photographed immediately and after various times as indicated after wounding. The number of cells that migrated into the cell-free zone was evaluated (B). The results are expressed as the total number of the migrated cells. These results are representative of two independent experiments performed in triplicate. *P < 0.05, significantly different from the vehicle-treated control at the indicated time. (C) Invasiveness of CL1–5 cells treated with or without DMSO was evaluated by the Matrigel-based transwell invasion assay. Columns, mean derived from three separate experiments done in triplicate; bars, SD. *P < 0.05, significantly different from the vehicle-treated control.