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. 2012 Apr 17;7(4):e33674. doi: 10.1371/journal.pone.0033674

Table 1. Univariate and Multivariate Cox Logistic Analysis of Factors Associated with Survival.

Clinical Variable Subset Hazard ratio (95% CI) P value
Univariate analysis (n = 293)
Age(years) ≥40 VS <40 1.20 (0.87–1.66) 0.277
Tumor homology Pure VS Mixed 0.86 (0.54–1.35) 0.504
FIGO stage IIb–IV VS I–IIa 2.86 (2.06–3.98) <0.001
Tumor mass size ≥4cm VS <4cm 3.02 (1.78–5.13) <0.001
Lymph node metastasis Negative VS Positive 0.34 (0.22–0.55) <0.001
Lymph-vascular space invasion Negative VS Positive 0.69 (0.38–1.25) 0.222
Depth of stromal invasion ≥2/3 VS <2/3 2.43 (1.13–5.21) 0.022
Neurone-specific enolase Positive VS Negative 1.32 (0.66–2.65) 0.432
Chromogranin A Positive VS Negative 1.78 (1.02–2.52) 0.034
Synaptophysin Positive VS Negative 1.22 (0.99–1.47) 0.057
Multivariate analysis (n = 293)
FIGO stage IIb–IV VS I–IIa 3.08 (2.05–4.63) <0.001
Tumor mass size ≥4cm VS <4cm 2.37 (1.28–4.36) 0.006
Chromogranin A Positive VS Negative 1.81 (1.12–2.91) 0.015

FIGO, International Federation of Gynecology and Obstetrics; CI, confidence interval. Bold indicates significant values.