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. 2001 Apr 24;98(10):5752–5757. doi: 10.1073/pnas.091096998

Figure 4.

Figure 4

Cytokine mRNA levels (normalized to β-actin mRNA levels) in lungs of mice infected with M. tuberculosis. (A) Cytokine mRNA at 14 and 28 days postinfection with NHN5 (filled symbols) and HN878 (open symbols): IFN-γ mRNA (□, ■) and IL-12 (○, ●). (B) mRNA at 28 days postinfection with NHN5 (filled bar) or HN878 (open bar). Uninfected mouse lungs had very low or undetectable levels of cytokine mRNA (not shown). (C) mRNA at 28 days postinfection with NHN5 (filled bar) or HN878 (open bar) or uninfected (cross-hatched bar). (C Inset) Relative levels of IFN-α mRNA in lungs of mice infected for 14 days with NHN5 (filled bar) or HN878 (open bar). Results are means of three independent experiments expressed as percentage activity relative to HN878-infected lungs. A, B, and C are single representative experiments.