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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Mucosal Immunol. 2012 Feb 1;5(3):258–266. doi: 10.1038/mi.2012.2

Figure 6. IL-6 prevents downregulation of anti-apoptotic molecules by influenza virus in neutrophils.

Figure 6

(a) Neutrophils from WT mice were cultured in the presence or absence of PR8 H1N1 virus at 1:10 neutrophil:virus (EIU) ratio with or without IL-6 (20 ng/ml). After 18 h, mitochondrial ROS was examined by staining with MitoSox-Red dye and flow cytometry analysis. Histogram profiles for neutrophils cultured in medium (thin line), with H1N1 virus (thick line) or H1N1 virus and IL-6 (filled) are shown. (b) Western blot analysis for Mcl-1 and Bcl-XL in neutrophils from WT mice treated as in (a). Actin was used as loading control.