Table 3.

Oral steroid therapy and intravenous steroid pulse therapy

	Kobayashi et al.	Pozzi et al.
Study design	Retrospective cohort study	Randomized controlled trial
Treatment groups	Oral steroid versus control	Steroid pulse versus control
Daily proteinuria	1.0–2.0 g	1.0–3.5 g
CCr	85 ± 14 versus 88 ± 13	70–111 ml/min (mean 91)
CCr (≥70 ml/min)	Renal survival rate: 100 versus 80% at 5 years (ns) 80 versus 34% at 10 years (p < 0.001)	Non-progression rate: 97 versus 53% at 10 years (p = 0.0003) Urinary complete remission rate: ~10% in the steroid pulse group

CCr creatinine clearance, ns not significant