Table 5.
Hotta et al. | Miura et al. | |
---|---|---|
Study design | Retrospective cohort study | Multicenter retrospective study |
Patients’ background |
Daily proteinuria: mean ± SD: 1.38 ± 1.17 g sCr: 0.96 ± 0.22 mg/dl |
|
CCr (>70 ml/min) | TSP versus steroid: CR rate: 59.7 versus 35.3%; p < 0.01 |
CR rate: 54.1% CR versus non-CR: Years from diagnosis until TSP therapy: mean ± SD 5.3 ± 5.2 versus 6.9 ± 6.8 (p = 0.02) Daily proteinuria 0.8 ± 0.8 versus 1.5 ± 1.6 (p < 0.0001) sCr 0.87 ± 0.34 versus 0.99 ± 0.40 (p = 0.006) |
CCr (<70 ml/min) |
Sato et al. Retrospective cohort study TSP versus steroid versus control Daily proteinuria: mean ± SD: 2.2 ± 1.9 versus 1.9 ± 0.9 versus 0.9 ± 0.6 CCr: 45.0 ± 15.1 versus 44.4 ± 14.9 versus 48.6 ± 19.7 Renal survival rate at 8 years: 82.8 versus 51.0 versus 45.1%: p = 0.017 (No significant difference in patients with sCr >2.0 mg/dl) |
Not available |
sCr serum creatinine, CCr creatinine clearance, CR clinical remission