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. 2011 Nov 16;16(2):195–201. doi: 10.1007/s10157-011-0552-8

Table 5.

A retrospective cohort study of tonsillectomy plus steroid pulse (TSP) therapy

Hotta et al. Miura et al.
Study design Retrospective cohort study Multicenter retrospective study
Patients’ background

Daily proteinuria: mean ± SD: 1.38 ± 1.17 g

sCr: 0.96 ± 0.22 mg/dl

CCr (>70 ml/min) TSP versus steroid: CR rate: 59.7 versus 35.3%; p < 0.01

CR rate: 54.1%

CR versus non-CR:

Years from diagnosis until TSP therapy: mean ± SD 5.3 ± 5.2 versus 6.9 ± 6.8 (p = 0.02)

Daily proteinuria 0.8 ± 0.8 versus 1.5 ± 1.6 (p < 0.0001)

sCr 0.87 ± 0.34 versus 0.99 ± 0.40 (p = 0.006)

CCr (<70 ml/min)

Sato et al.

Retrospective cohort study

TSP versus steroid versus control

Daily proteinuria: mean ± SD: 2.2 ± 1.9 versus 1.9 ± 0.9 versus 0.9 ± 0.6

CCr: 45.0 ± 15.1 versus 44.4 ± 14.9 versus 48.6 ± 19.7

Renal survival rate at 8 years: 82.8 versus 51.0 versus 45.1%: p = 0.017

(No significant difference in patients with sCr >2.0 mg/dl)

Not available

sCr serum creatinine, CCr creatinine clearance, CR clinical remission