FIG. 3.

14S,21R-diHDHA treatment promotes anti-inflammatory action of mMSCs after renal ischemia/reperfusion injury. Immunostaining against Gr-1, F4/80, CD11c, and MHCII were performed on kidney sections collected at days 1 and 3 post-I/R. (A) Representative kidney sections showing Gr-1+ neutrophils, F4/80+ macrophages, and CD11c+MHCII+ DCs (arrows) at day 1 or 3 post-I/R (magnification, ×200; scale bar=50 μm). Quantification of Gr 1+ neutrophils (B), F4/80+ macrophages (C), and CD11c+ MHCII+ DCs (D) in kidney. Results are expressed as mean±SEM, n=6. *P<0.05 versus sham, ^†P<0.05 versus I/R control, ^‡P<0.05 versus MSCs. Color images available online at www.liebertonline.com/scd