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. Author manuscript; available in PMC: 2012 Apr 18.
Published in final edited form as: JAMA. 2009 Apr 8;301(14):1460–1467. doi: 10.1001/jama.2009.458

Table 2.

Mean scores (and standard deviations) on measures of secondary outcomes across time for patients in CBT or EUC.

Treatment Effect Treatment Effect Time Effect Treatment x Time Effect

Baseline (N = 134) 3-Mo (N = 115) F p d (95 % CIs) 6-Mo (N = 95) 9-Mo (N = 96) 12-Mo (N = 92) 15-Mo (N = 94) F p F p F p
PSWQ CBT 53.3 (10.6) 45.6 (8.9) 19.01 <.00 01 .85 (.49, 1.20) 44.1 (9.4) 44.0 (8.1) 42.5 (9.3) 42.8 (9.1) 15.12 .0002 4.53 .002 1.88 .12


EUC 57.6 (10.9) 54.4 (10.6) 52.7 (10.7) 50.4 (11.0) 50.9 (12.0) 50.8 (11.8)

GADSS CBT 11.4 (3.6) 8.6 (3.6) 1.77 .19 .27 (−.07, .61) 8.6 (3.9) 8.6 (4.3) 8.5 (3.8) 8.7 (4.7) 1.75 .19 .10 .98 .14 .97


EUC 11.3 (3.4) 9.9 (4.5) 9.7 (4.7) 9.6 (5.1) 9.2 (4.7) 9.5 (4.5)

SIGH-A CBT 19.4 (7.7) 15.1 (7.5) 1.45 .23 .13 (−.21, .47) 14.5 (7.7) 13.6 (8.0) 13.2 (6.6) 13.9 (8.2) 2.64 .11 .70 .60 .77 .55


EUC 19.1 (7.9) 16.1 (7.4) 16.2 (8.6) 15.9 (8.8) 15.7 (7.9) 15.1 (8.0)

BDI CBT 16.3 (8.0) 10.2 (7.0) 5.9 .02 .34 (.00, .68) 9.3 (7.1) 9.7 (7.2) 8.5 (6.8) 8.3 (7.3) 4.67 .03 2.11 .08 1.66 .16


EUC 16.4 (9.5) 12.8 (8.3) 10.9 (8.4) 10.3 (7.0) 10.1 (6.9) 11.4 (7.3)

SF-12 MCS CBT 42.4 (10.0) 49.6 (8.9) 7.45 .008 .48 (.14, .83) 51.2 (8.4) 48.4 (9.3) 50.2 (8.0) 50.3 (8.4) 5.42 .02 1.61 .18 .81 .52


EUC 41.7 (9.5) 45.3 (9.4) 47.4 (10.4) 48.1 (10.3) 47.5 (10.2) 47.0 (10.6)

SF-12 PCS CBT 44.0 (8.5) 41.6 (7.9) .03 .87 .08 (−.26, .42) 42.4 (7.7) 42.7 (7.6) 41.5 (6.7) 42.1 (7.1) .20 .66 .56 .69 .26 .90


EUC 44.3 (8.2) 41.8 (9.6) 40.5 (10.2) 42.6 (8.5) 41.7 (8.3) 41.8 (7.9)

Abbreviations: CBT, cognitive behavior therapy; EUC, enhanced usual care; BDI, Beck Depression Inventory – 11; Medical Outcomes Study Short Form; MCS, Mental Component Scale; PCS, Physical Component Scale; QOLI; Quality of Life Intervention.

NOTE: All means are observed means (corresponding Ns are noted).