Figure 3.
Effects of 24 hour fasting on both control and liver-specific expression of GPR109A. C57BL/6 mice were injected intraperitoneally with 1x1012 genome copies AAV2/8 GPR109A or control AAV2/8 Null. After 11 weeks of virus injection, chow-fed mice were subjected to 24 hour fasting; plasma levels of β– hydroxybutyrate (A), total cholesterol (B) and HDL-C (C) were measured. Data are expressed as mean ± SEM, n=7. *P<0.05 compared with 4 hours fasting, #P <0.05, ##P<0.01 compared with AAV-Null.