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. 2004 Nov;10(11):1895–1899. doi: 10.3201/eid1011.040476

Table. Comparison of antimicrobial drug use within and outside a trachoma programa.

DDD/person/
year to all ages Prescriptions/person/
year to preschool children
Antimicrobial pressure from pharmacies
All antimicrobial drug prescriptions (from survey) 3.0 1.8
Antichlamydial prescriptions (from survey) 2.0 1.2
Antimicrobial pressure from trachoma program
Annual azithromycin treatment with 100% coverage (theoretical) 2.3 1
Annual azithromycin treatment with 80% coverage (theoretical) 1.9 0.8

aPharmacy survey data showing the total quantity of antimicrobial drugs used in Geta subdistrict and the proportion of antimicrobial drug with antichlamydial activity. An annual trachoma program theoretically gives 1 g of azithromycin to every adult (3.3 DDDs) and a lower dosage to children, averaging approximately 2.3 DDDs per person for all ages. We estimate from a mathematical model that mass antimicrobial treatment every 1.7 years would be sufficient to eventually eliminate ocular chlamydial infection from this region (13). DDD, defined daily dose, the average adult daily dosage for a drug's primary indication.