(b)

Dose	Sodium (mmol/L)	Pottasium (mmol/L)	Chloride (mmol/L)	CO2 (mmol/L)	Anion gap (mmol/L)	Urea (mmol/L)	Creatinine (μmol/L)
Vehicle (CMC)	141.87 ± 0.42	4.83 ± 0.14	105.78 ± 0.67	23.33 ± 0.41	18.00 ± 0.25	7.95 ± 0.33	41.76 ± 2.75
LD (2 g/kg)	142.07 ± 0.56	4.55 ± 0.16	105.85 ± 0.65	22.65 ± 0.42	17.49 ± 0.46	7.97 ± 0.49	42.00 ± 2.36
HD (5 g/kg)	142.15 ± 0.47	4.63 ± 0.18	107.03 ± 0.53	21.96 ± 0.75	17.67 ± 0.48	8.31 ± 0.68	43.13 ± 2.24

Values expressed as mean ± S.E.M. There are no significant differences between groups. Significant value at P < 0.05.