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. 2011 Oct-Dec;1(4):456–461. doi: 10.4103/2045-8932.93544

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Copyright: © Pulmonary Circulation

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Anti-Schistosoma mansoni-soluble egg antigen (SEA) antibody detects S. mansoni eggs in infected mouse lung and human intestine. (a and b) Mice with S. mansoni eggs administered intravenously develop peri-egg granulomas. The eggs can be visualized with the polyclonal anti-SEA antibody in postimmunization serum, but no significant signal is seen when antibodies in preimmunization rabbit serum are used. (c and d) Similarly, postimmunization serum but not preimmunization serum detects S. mansoni eggs in infected human intestines. Eggs are marked with a “*”; blue is DAPI; all scale bars are 100 μm.