Figure 3.

Inh I and Inh II do not affect UVB-induced AP-1 DNA binding. JB6 Cl 41 cells were treated, nuclear proteins were extracted, and electrophoretic mobility-shift assays were carried out as described in the text. (A) UVB strongly induces AP-1 DNA binding (lane 3), and the binding is specific as indicated by the effective competition of a 10-fold excess of the unlabeled AP-1 probe (lane 1). Inh I or Inh II has little effect on UVB-induced AP-1 DNA binding (lanes 4 and 5). (B) Densitometry analysis of A from three independent experiments.