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. 2011 Nov 17;6(5):961–974. doi: 10.1038/ismej.2011.160

Table 3. External to internal branch length ratio test, implemented in clonal frame.

Population External/ internal branch length ratio (95% confidence interval) Significance
Phylotype I 2.528 (1.413–4.271) 0.0013**
Phylotype II 1.367 (0.988–1.810) <0.001***
Phylotype IIA 1.918 (1.166–3.038) 0.0016**
Phylotype IIB 1.362 (0.837–2.281) 0.037*
Phylotype III 2.647 (1.480–4.577) <0.001***
Phylotype IV 1.331 (0.832–2.189) 0.150 (NS)

Abbreviation: NS, not significant; *, significant; **, highly significant; ***, very highly significant. If the ratio is significantly higher than expected, the inferred genealogy is considered as unexpectedly ‘star-like', which is consistent to either an expansion of the population size or the acquisition of a fitness advantage early in the history of the sample (Didelot and Falush, ClonalFrame UserGuide version 1.1; den Bakker et al. (2008).