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. 2011 Dec 1;6(5):939–950. doi: 10.1038/ismej.2011.167

Figure 2.

Figure 2

Comparison of amino-acid sequence of the sensory input domain of the DSF sensor PA1396 from different CF isolates of P. aeruginosa. The amino-acid sequences shown represent residues 1–187 of PA1396. The top panel describes the predicted transmembrane segments found in the input of PA1396. The sequences were obtained by PCR, cloning and sequencing of full-length PA1396 genes from 40 clinical isolates of P. aeruginosa extracted from the sputum from CF patients. Sequences of PA1396 from the model P. aeruginosa strains PAO1, PA14 and PA7 are included for comparative purposes. Sequences were aligned using ClustalW and presented using BIOEDIT. The majority of alterations at different positions appear to be of a conservative nature.