Fig. 5.

Dgat2 and Mtp mRNA silencing following an individual or combination treatment. Dgat2 (A, C) and Mtp (B, D) mRNA expression compared with control-treated groups on day 14 (A, B) and day 28 (C, D). A single 1.5:1.5 mg/kg or 3 mg/kg dose was administered to the day 14 groups. A 1.5:1.5 or 3 mg/kg dose was administered on days 0 and 14 to the day 28 groups. Cntrl represents the control siRNA treatment. Groups labeled with two treatments were given a combination dose. Data are shown as mean % expression (bars) ± SD bars (N = 8 per group).