Fig. 3.

Macrophage CLC of sera from subjects before, immediately after, and two days after LDL-apheresis. Cellular cholesterol content of THP-1 cells incubated in the absence or presence of 5% (v/v) serum was measured as described in Methods. Each bar represents the average ± SD cholesterol content of cells exposed to patient serum harvested before LDL-apheresis (filled bar), immediately after LDL-apheresis (horizontal lines bar), and two days after LDL-apheresis (vertical lines bar) (n = 6). Intracellular cholesterol content is expressed as micrograms of cholesterol per milligrams of protein. Statistical analysis was estimated by unpaired two tailed t-test; ***P < 0.001.