Table 3. Stratified analysis of rs12133337 effects on the immune response to hepatitis B vaccination by BMI.

	BMI ≥25 kg/m2				BMI <25 kg/m2
1st stage
	HR n = 63 (100%)a	LR n = 52 (100%)b	P c	OR (95%CI)c	HR n = 151 (100%)a	LR n = 55 (100%)b	P c	OR (95%CI)c
TT	48 (76.2)	40 (76.9)	0.98	1.01	135 (89.4)	40 (72.7)	0.003	3.58
CT+CC	15 (23.8)	12 (23.1)		(0.98–1.12)	16 (10.6)	15 (27.3)		(1.53–8.38)

^aHR: High responder (anti-HBs ≥1,000 mIU/ml);

^bLR: Low responder (anti-HBs 10–99 mIU/ml).

^c P-values and OR (95% CI) were adjusted for age, gender, and smoking history.

^d P-values and OR (95% CI) were adjusted for age, gender, smoking history, and vaccines.