Figure 1. T-cadherin expression in islets delineates intracellular granules and the pancreatic vasculature. (A) Confocal micrographs of WT mouse pancreas and (B) isolated human islet. (C) T-cadherin in mouse islet cells does not associate with cell boundaries. (D) T-cadherin in mouse skeletal muscle associates with myofiber surfaces. T-cadherin in green (A–D). Insulin in red (A and B). Actin (phalloidin) in red (C). DAPI in blue (A–E). (E) T-cadherin (green) is also found on blood vessels in the exocrine pancreas (CD31-red). (F) Adiponectin (green) is localized to blood vessels (CD31-red) in the islet periphery (insulin-blue).