Figure 2.
Characterization of humoral immune responses induced by Bac-RSV/G vaccine. (A) BALB/c mice were immunized twice with 2×108 PFU of recombinant baculovirus (Bac-RSV/G or Bac-control) via intranasal route, and systemic anti-RSV IgG antibody titers were measured by serum ELISA two weeks after boosting. (B) Secretory IgA titers were measured in the BAL fluid for each immune group five days after RSV challenge. The results represent Log2 endpoint values from four to five individual mice. Data are representative of at least three independent experiments and data are average±SEM, n=4~5 mice per group. N.D., not detected.