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Immune protection from respiratory RSV challenge by vaccination with Bac-RSV/G. Each group of immune mice was challenged with 1×106 PFU of RSV A2 at 4 weeks after immunization and the level of viral replication in the lungs was determined by plaque assay at day 5. Results are expressed as the mean±SEM from 4 to 5 mice per group. The limit of detection is 200 PFU/g of lungs. N.D., not detected.
