Figure 7.

Bac-RSV/G immunization promotes neither lung eosinophilia nor vaccine-enhanced illness. (A) Mice were immunized and challenged as in Fig. 3. BAL was performed five days after RSV challenge, and BAL cells were stained with antibodies to CD45, Siglec-F, and CD11c, and eosinophils were quantitated among CD45⁺-gated cells. Average percentages of Siglec-F+CD11c-cells among total CD45⁺ cells represent mean±SD (n=6). The results are a representative of three independent experiments. (B) The same group of immune mice were challenged with RSV and then weighed each day. Results are expressed as the mean±SEM from 5 mice for each group. All data are representative of at least two independent experiments.