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. Author manuscript; available in PMC: 2012 Apr 19.
Published in final edited form as: Biochem J. 2009 Nov 11;424(2):179–189. doi: 10.1042/BJ20090992

Figure 4. Characterization of chimaeric zebrafish/human α5β1-1 blade swap integrins.

Figure 4

Binding of wild-type huα5β1-1, and zfα5(huW1-3)β1-1, zfα5(huW2-4)β1-1 and zfα5(huW1-4)β1-1 blade swap receptors to (A) 50K fragment of human fibronectin and (B) 70K fragment of zebrafish fibronectin. No significant binding of wild-type zfα5β1-1 to 50K was observed in the same assay (not shown).