Table 2.
Index acute myocardial infarction, initial presentation and management
| Whole population (N=3079), N (%) | NSTEMI (N=1306), N (%) | STEMI or presumed new LBBB (N=1773), N (%) | p Value | |
| Admission parameters | ||||
| Typical chest pain | 2568 (83) | 1036 (79) | 1532 (86) | <0.001 |
| Initial Killip class | <0.001 | |||
| I | 2457 (83) | 1023 (81) | 1434 (84) | |
| II | 301 (10) | 124 (10) | 177 (10) | |
| III | 153 (5) | 91 (7) | 62 (4) | |
| IV | 63 (2) | 21 (2) | 42 (2) | |
| GRACE score | 142±37 (n=2879) | 138±38 (n=1216) | 145±36 (n=1663) | <0.001 |
| Time delays (minutes) | ||||
| Time from onset to first call or contact Median [25th; 75th percentiles] | 90 [30; 300] | 105 [30; 390] (n=1257) | 74 [30; 240] (n=1727) | <0.001 |
| Procedures and management | ||||
| Coronary angiography | 2884 (94) | 1185 (91) | 1699 (96) | <0.001 |
| PCI | 2380 (77) | 859 (66) | 1521 (86) | <0.001 |
| Fibrinolysis in STEMI patients | ||||
| No | 1532 (86) | |||
| Pre-hospital | 137 (8) | |||
| In-hospital | 104 (6) | |||
| Primary PCI in STEMI patients | ||||
| Performed | 1073 (64) | |||
| Intended | 1171 (70) | |||
| Coronary artery bypass grafting | 89 (3) | 66 (5.1) | 23 (1.3) | <0.001 |
| Medications in first 48 h | ||||
| Aspirin | 2956 (96) | 1256 (96) | 1700 (96) | 0.686 |
| Clopidogrel | 2474 (80) | 1139 (87) | 1335 (75) | <0.001 |
| Prasugrel | 743 (24) | 179 (14) | 564 (32) | <0.001 |
| Glycoprotein IIb/IIIa inhibitors | 1062 (34.5) | 318 (24) | 744 (42) | <0.001 |
| Low molecular weight heparin | 1887 (61) | 784 (60) | 1103 (62) | 0.220 |
| Unfractionated heparin | 1705 (55) | 656 (50) | 1049 (59) | <0.001 |
| Fondaparinux | 518 (17) | 247 (19) | 271 (15) | 0.008 |
| Bivalirudin | 102 (3) | 21 (2) | 81 (5) | <0.001 |
| Statin | 2704 (88) | 1114 (85) | 1590 (90) | <0.001 |
| β-blocking agents | 2439 (79) | 1015 (78) | 1424 (80) | 0.079 |
| ACE-I or ARB | 1949 (63) | 804 (62) | 1145 (65) | 0.086 |
ARB, angiotensin II receptor blocker; CABG: coronary artery bypass graft surgery; CAD, coronary artery disease; GRACE, Global registry of acute coronary events; LBBB, left bundle branch block; MI, myocardial infarction; NSTEMI, non-ST-segment-elevation myocardial infarction; PCI, percutaneous coronary intervention; STEMI, ST-segment-elevation myocardial infarction; TIA, transient ischaemic attack.