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. Author manuscript; available in PMC: 2013 Apr 12.
Published in final edited form as: J Med Chem. 2012 Apr 3;55(7):3535–3545. doi: 10.1021/jm300214e

Figure 6.

Figure 6

Effects of the indole enantiomers, 9g and 9h, on neuronal survival in the spinal cords of NSV-infected mice. Silver staining of tissue sections prepared from the lumbar spinal column was used to identify the ventral nerve roots and the motor neuron axons they carry. (A) A representative specimen from an uninfected animal is shown, with the L4 and L5 ventral nerve roots identified (marked with an *). (B) Quantification of axonal density in these lumbar ventral nerve roots shows relative neuronal sparing in 9h-treated animals compared to vehicle- or 9g-treated controls. Statistical differences (*p<0.05) were determined using unpaired Student’s t-tests.