Scheme 1.
Preparation of Thieno[3,2-b]pyrrole Analogs of 1a
aReagents and Conditions: (a) K2CO3, DMF, R1Cl or Ph3P, DIAD, R1OH, THF. (b) KOH, aq EtOH, 40 °C. (c) ethyl isonipecotate, EDC, HOBt, DIEA, DCM, RT. (d) HNR2R3, EDC, HOBt, DIEA, RT.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.