Asymmetric output from corticospinal to layer 5A corticostriatal neurons. A, Example responses to corticospinal stimulation, recorded in a pair of untransfected corticospinal (SPI, blue) and layer 5A corticostriatal (5A-STR, red) neurons. B, Group analysis. Lines connect data points from individual pairs. Group means (±SEM) are plotted to either side. C, Example responses to corticostriatal stimulation, recorded in a pair of untransfected corticospinal (blue) and layer 5A corticostriatal (red) neurons. D, Group analysis. Lines connect data points from individual pairs. Group means (±SEM) are plotted to either side.