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. Author manuscript; available in PMC: 2012 Apr 19.
Published in final edited form as: Int J Oncol. 2011 Apr 21;39(1):111–119. doi: 10.3892/ijo.2011.1014

Figure 4.

Figure 4

Both valproic acid and TSA increase caspase 3/7 activity. (A) Cells were treated with valproic Acid (0.1–10 mM) or vehicle control for 12 or 24 h before the measurement of caspase 3/7 activity. (B) Cells were treated with TSA (5–1000 nM) or vehicle control (DMSO) for 12 or 24 h before the measurement of caspase 3/7 activity. Caspase 3/7 activity was determined using Caspase-Glo 3/7 assay reagent (Promega) according to manufacturer’s protocol. Values represent the mean of luminescence signals of three independent experiments with standard deviations. *P<0.01

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