Figure 7.
Both TSA and valproic acid induce acetylation of p53 in VCaP cells. (A) Western blot assays were performed on VCaP cells incubated for 12 or 24 h at the indicated concentrations of valproic acid. Blot with anti-acetylated p53-Lys 373 (top), anti-p53 (middle), or anti-β-actin (bottom) are shown. (B) Western blots were performed on VCaP cells incubated for 12 or 24 h at the indicated concentrations of TSA. Blot with anti-acetylated p53-Lys 373 (top), anti-p53 (middle), or anti-β-actin (bottom) are shown.