Figure 6.
Change in synaptic input (defined as the difference in input between the blend response and the average response to the single components at low concentration, multiplied by the corresponding synaptic weights) for AL neurons of different blend interaction types (μ ± SEM for 100 model realizations). (A) Total change in synaptic input arriving to neurons that respond with excitation. (B) Total change in synaptic input arriving to neurons that respond with inhibition. The p values for cases in which we found significant differences in the t-test (p ≤ 0.01, after Bonferroni correction) are listed in the following. In panel A: suppression vs. hypoadditivity p < 1 × 10−6; suppression vs. linear addition p < 1 × 10−6; suppression vs. synergy p < 1 × 10−6; hypoadditivity vs. linear addition p = < 1 × 10−6, hypoadditivity vs. synergy p < 1 × 10−6. In panel B: suppression vs. hypoadditivity p < 1 × 10−6; suppression vs. linear addition p < 1 × 10−6; hypoadditivity vs. linear addition p = 3.8 × 10−4.