NCI-CTC AE v3.0 |
loss of deep tendon reflexes or paresthesia, including tingling, but not interfering with function |
objective sensory alteration or paresthesia, including tingling, interfering with function, but not with activities of daily living |
sensory alteration or paresthesia interfering with activities of daily living |
permanent sensory losses that are disabling |
Questions |
Sample answers for each toxicity grade |
Do you have problems tying your shoe laces, buttoning your shirts, fastening buckles or pulling up zippers? |
“No, I might feel some tingling in my hands, but I have no problems tying laces, buttoning shirts, fastening buckles or pulling up zippers” |
“It is a bit harder than before, but I can still tie laces, button shirts, fasten buckles or pull up zippers” |
“I have severe difficulties tying shoe laces, buttoning shirts, fastening buckles or pulling up zippers” or “I cannot tie laces, button shirts, fasten buckles or pull up zippers anymore” |
“I haven’t been able to tie laces, button shirts, fasten buckles or pull up zippers for weeks” |
Do you have problems writing? |
“No, I might feel some tingling in my hands, but I have no problems writing” |
“It is a bit harder than before, but I can still write” |
“I have severe difficulties writing” or “I cannot write anymore” |
“I haven’t been able to write for weeks” |
Do you have problems putting on your jewelry or your watch? |
“No, I might feel some tingling in my hands, but I have no problems putting on my jewelry or my watch” |
“It is a bit harder than before, but I can still put on my jewelry or my watch” |
“I have severe difficulties putting on my jewelry or my watch” or “I cannot put on my jewelry or my watch anymore” |
“I haven’t been able to put on my jewelry or my watch for weeks” |
Do you have problems walking? |
“No, I might feel some tingling in my feet, but I have no problems walking” |
“It is a bit harder than before, but I can still walk” |
“I have severe difficulties walking” or “I cannot walk anymore” |
“I haven’t been able to walk for weeks |