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Effect of lack of p53 on the nuclear levels of BVR-A, Nrf-2, and NF-kB in mice brain. (A) BVR-A, (B) Nrf-2, and (C) NF-kB protein levels were measured in the nuclear fraction isolated from the brain of wt and p53(−/−) mice as described under Materials and Methods section. Representative gels are shown. Data are expressed as mean±SD (n=6 animals per group). *p<0.05, and **p<0.01 versus wt group.
