Table 3.
Combined Association Analysis in The Third Sample Set
| Third Sample Set |
Combined Analysis |
||||||
| Gene | Genotype Counts |
Mutation Frequency |
Gene Based |
||||
| AA Change | SCZ | CONT | SCZ | CONT | OR | P value | |
| KALRN | R410H | 0/0/1481 | 0/0/1484 | 0 | 0 | 2.07 | .003 |
| KALRN | Q770K | 0/0/1486 | 0/0/1490 | 0 | 0 | ||
| KALRN | T1207M | 0/7/1477 | 0/3/1482 | 0.0024 | 0.0010 | ||
| KALRN | P2255T | 0/31/1448 | 0/15/1473 | 0.0105 | 0.0050 | ||
| KALRN | A2382V | 0/7/1473 | 0/4/1480 | 0.0024 | 0.0013 | ||
| EPHB1 | F151S | 0/0/1478 | 0/0/1484 | 0 | 0 | 1.09 | .438 |
| EPHB1 | D375N | 0/0/1483 | 0/0/1490 | 0 | 0 | ||
| EPHB1 | D577N | 0/0/1486 | 0/2/1483 | 0 | 0.000673 | ||
| EPHB1 | R637C | 0/4/1477 | 0/4/1478 | 0.0014 | 0.0014 | ||
| EPHB1 | R905C | 0/15/1458 | 0/12/1466 | 0.0051 | 0.0041 | ||
| EPHB1 | T981M | 0/5/1481 | 0/4/1484 | 0.0017 | 0.0013 | ||
Note: Abbreviations are explained in the first footnote to table 1. P values were calculated by Fisher exact test (1 tailed).