Figure 5. (A) G values for top- and poorly-ranked predictions that were experimentally tested using fluorescence polarization.

Predictions plotted in green denote that the binding affinity was higher than the best previously known hexamer (). Horizontal line represents average G for plotted sequences. Sequence information and binding data can be found in Tables 1 and 2. (B) Ensemble of top 100 conformations for the peptide (kCAL01: WQVTRV, orange sticks) with tightest binding to CAL (gray ribbon).