Table 2.
mRNAs that are more abundant in wild-type-infected than in phoP∷Tn10 mutant-infected macrophages*
| Ratio† | SE | |
|---|---|---|
| Inflammatory | ||
| CD9 antigen (p24) | 2.1 | 1.7 |
| E74-like factor 1 (ets domain transcription factor) | 2.5 | 1.5 |
| Leukocyte immunoglobulin-like receptor (ILT3) | 1.9 | 1.4 |
| Cathepsin D (lysosomal aspartyl protease) | 2.1 | 1.4 |
| Cell death/survival | ||
| STAT-induced STAT inhibitor 3 (SSI-3) | 2.2 | 1.5 |
| PIM-1 serine/threonine kinase | 2.0 | 1.5 |
| Tumor necrosis factor-α-induced protein 3 (A20) | 1.9 | 1.7 |
| Cell cycle | ||
| Cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 2.0 | 1.5 |
| v-myb viral oncogene homolog-like 2 | 1.9 | 1.4 |
| Dihydrofolate reductase | 1.9 | 1.4 |
| Other | ||
| Thrombospondin 1; ECM, secreted, TGFB activator | 1.9 | 1.5 |
| Contactin 1, cell adhesion | 2.0 | 1.6 |
| Solute carrier family 15 (H+/peptide transporter) | 3.0 | 1.7 |
| Human rhotekin mRNA, Rho GTPase inhibitor | 2.2 | 1.6 |
| Carbonic anhydrase-related protein 10 | 2.6 | 1.5 |
| Ceruloplasmin (ferroxidase) copper scavanger | 1.9 | 1.4 |
| UDP glycosyltransferase 2 family, polypeptide B4 | 1.9 | 1.6 |
| Fatty acid binding protein 4, adipocyte | 2.6 | 2.2 |
| Fibroblast activation protein-α | 2.0 | 1.7 |
| α-methylacyl-CoA racemase | 2.3 | 1.6 |
| Suppression of tumorigenicity 14 | 2.1 | 1.7 |
*
False positive rate = 5.9%.
†
Relative expression levels of wild-type-infected macrophages and phoP∷Tn10 mutant-infected macrophages.