Immunoblot analysis of p38: (A) Total p38 density (arbitrary unit); (B) Phospho-p38 (Thr180/Tyr182) density (arbitrary unit); (C) P38 phosphorylation ratio (arbitrary unit), obtained by A normalized by B. Open columns for sham groups, closed columns for TAC groups. *, p<0.05 compared to the respective sham. (D) Representative immunoblot strips for p38, phosphor-p38 and calsequestrin (CSQ). Samples are labeled as the number of weeks post-surgery followed by the type of surgery (S for sham, T for TAC). Sample size was 5 – 6 for sham mice and 8–10 for TAC mice at each time point.