Table 2.
Pathologic characteristics and treatment of adenocarcinoma (AC) vs. adenosquamous carcinoma (ASC)
| AC | ASC | P-value* | |
|---|---|---|---|
| Stage (%) | <0.001 | ||
| I | 25497 (24.4%) | 6 (6.4%) | |
| II | 37461 (35.8%) | 28 (30.1%) | |
| III | 27104 (25.9%) | 25 (26.9%) | |
| IV | 14567 (13.9%) | 34 (36.6%) | |
| Histological Grade | <0.001 | ||
| Well differentiated | 10207 (9.6%) | 1(1.1%) | |
| Moderately differentiated | 74283 (70.1%) | 27(28.7%) | |
| Poorly differentiated | 20928 (19.7%) | 62(66.0%) | |
| Undifferentiated | 597 (0.6%) | 4(4.2%) | |
| Location | 0.01 | ||
| Proximal and transverse colon | 48912 (44.0%) | 56(56.3%) | |
| Descending colon | 4891 (4.4%) | 0(0.0%) | |
| Sigmoid colon | 26457 (23.8%) | 14(14.1%) | |
| Rectosigmoid | 9672 (8.7%) | 8(8.5%) | |
| Rectum | 19676 (17.7%) | 18(18.3%) | |
| Unknown | 1556 (1.4%) | 3(2.8%) | |
| Radiation | 0.760 | ||
| No radiation | 100036 (90.0%) | 90(90.9%) | |
| Radiation | 11128 (10.0%) | 9(9.1%) | |
| Chemotherapy | 0.101 | ||
| No | 72316 (65.1%) | 55(55.6%) | |
| Yes | 34917 (31.3%) | 41(41.4%) | |
| Unknown | 3931 (3.6%) | 3(3.0%) | |
| Surgery | 0.003 | ||
| Local excision | 5386 (4.8%) | 1 (1.0%) | |
| Partial colectomy | 51267 (46.1%) | 38 (38.4%) | |
| Subtotal colectomy | 43353 (39.0%) | 41(41.4%) | |
| Total/proctocolectomy | 10291 (9.3%) | 19 (19.2%) | |
| Unknown colectomy | 867 (0.8%) | 0 (0.0%) |
*
P-value < 0.5 considered significant