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Urinary PGE2 excretion (A) and renal medullary mRNA expression of mPGES-1 (B), cyclooxygenase (COX)-1 (C), COX-2 (D), mPGES-2 (E), and cPGES (F) in mPGES-1 WT and KO mice following 24-h WD. Urinary PGE2 was determined by EIA and renal medullary gene expression by qRT-PCR; n = 6–9/group. Values are means ± SE.
